Mucosal model

  • MCTT HCE™Corneal model
    (2019 OECD TG Registration)


    MCTT HCE™ Eye
    Irritation Test Protocol


    MCTT HCE™ Eye Irritation Test Protocol.pdf

    Characteristics
    • Consists of human corneal and conjunctiva
      cells which are not genetically modified
    • Possesses a similar composition to the human cornea
    • Composed of 3 differentiated corneal cell layers
    • Expresses mucin, a cornea-specific marker
    • Safe against viral and bacterial infections
    Applications
    • Preclinical studies for ophthalmic drugs
    • Irritation tests of cosmetics and medical devices etc. on the eye
    • Corneal permeation/metabolism

  • SoluOral™Oral mucosa model

    Characteristics
    • Consists of human oral mucosal epithelial cells which are not genetically modified
    • Similar composition to human oral mucosa
    • Expresses non-keratinized oral mucosa specific markers
    • Safe against viral and bacterial infections
    Applications
    • Oral Irritation
    • Safety Test on oral care products
    • Evaluation of the bio-compatibility of dental materials

  • SoluAirway™Airway mucosa model

    Characteristics
    • Consists of human respiratory cells which are not genetically modified
    • Similar structure to the human upper airway mucosa
    • Contains mucin-secreting cells
    • Pseudostratified ciliated epithelium
    • Safe against viral and bacterial infections
    Applications
    • Research on upper airway diseases such as asthma and cystic fibrosis etc.
    • Inhalation toxicity tests on air pollutants and nanoparticles etc.
    • Research on drug delivery via nose